Lijecnicki vjesnik 2016;138(5-6)
GUIDELINES FOR THE PREVENTION, DETECTION AND THERAPY OF VITAMIN D DEFICIENCY IN ADULTS
Darija Vranešić Bender, ZLATKO GILJEVIĆ, Vesna Kušec, Nadica Laktašić Žerjavić, Marija Bošnjak Pašić, Eduard Vrdoljak, Dina Ljubas Kelečić, Željko Reiner, Branimir Anić, Željko Krznarić
Abstract
It is estimated that over one billion of people around the globe have low serum values of vitamin D, therefore, we can consider vitamin D deficiency as a pandemic and public health problem. Geographic position of Croatia, especially the continental part of the country, is a risk factor for the development of deficiency of vitamin D in the population. The aim of these guidelines is to provide the clinicians with easy and comprehensive tool for prevention, detection and therapy of vitamin D deficienncy in healthy population and various groups of patients. They were made as a result of collaboration of clinicians of different backgrounds who are dealing with patients at risk of vitamin D deficiency. These guidelines are evidence-based, according to GRADE-system (Grading of Recommendations, Assessment, Development and Evaluation), which describes the level of evidence and strength of recommendation. The main conclusions address the recommended serum vitamin D values in the population which should be between 75 and 125 nmol/L and defining recommended preventive and therapeutic dosages of vitamin D in order to reach the adequate levels of serum vitamin D.