Lijecnicki vjesnik 2012;134(5-6)

BREAST CANCER METASTASES TO THE STOMACH AND COLON: TWO CASE REPORTS

Roland Pulanić, Marko Jelavić, MARINA PREMUŽIĆ, Milorad Opačić, JASMINKA JAKIĆ-RAZUMOVIĆ, Ranka Padovan-Štern, Damir Vrbanec

Abstract

Breast cancer has a high potential for metastasis, usually to the lungs, bones, liver and lymph nodes. Metastases in the hollow organs of the digestive system are rare and mainly affectes the stomach and colon. They are characterized by very different clinical and radiological manifestations. We have warned that the initial unrecognized breast cancer can appear as a primary tumor of the stomach and colon, and only a histopathological analysis reveales that it is a metastatic breast cancer. Metastases to the stomach or intestine involve deep layer of the mucosa and pathohistological findings of standard biopsy sample can be falsely negative, despite positive imaging technique (abdominal ultrasound and MSCT, endoscopic ultrasound) that indicate the tumor process. That’s why we emphasize the importance of endoscopic mucosal resection in the detection of malignant process of deeper layers of the gastric mucosa and deep intestinal mucosal biopsies with postoperative analysis of its walls.

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