Lijecnicki vjesnik 2003;125(5-6)

VACCINATION AGAINST HEPATITIS B ON CHRONIC HAEMODIALYSIS

Vedran Kovačić, Milenka Šain, Valentina Vukman*

Abstract

Summary. Patients on chronic haemodialysis (PCHD) respond less well to vaccination with recombinant hepatitis B virus superficial antigen (HbsAg) because of immunity disorders in uraemic patients. Today many schemes and vaccination modi- fication for nonresponding PCHD are proposed. The reaction on vaccination with HbsAg is weaker in those PCHD who had diabetes, older age and insufficient nutritive parameters. In those patients some alternative schemes of vaccinating for nonre- spondering PCHD must be considered, especially one of the proposed intradermal ways of vaccine inoculation.

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